Follows a criminal gang in Rome that has a near monopoly of the city's heroin trade. Besides their internal feuding, the gang has to deal with the Camorra and Sicilian Mafia that both supply its heroin, the police led by Commissioner Scialoja and the Italian secret services.

Vinicio Marchioni, Alessandro Roja, Andrea Sartoretti, Mauro Meconi, Riccardo De Filippis, Orlando Cinque, Daniela Virgilio, Roberto Infascelli, Tommaso Sacco